He made his acting debut in Godmother (1999). He made his debut as a co-lead actor in the Hindi film Style (2001), this was followed by supporting roles in hit films like, Rang De Basanti (2006), Golmaal (2006), Life in a... Metro (2007) and 3 Idiots (2009), his next hit film as a lead was Ferrari Ki Sawaari (2012), which got him critical acclaim.
Sharman Joshi belongs to a Gujarati family of actors and performing artists. His father, Arvind Joshi is a veteran of Gujarati theatre, while his aunt Sarita Joshi (Bhosle), sister and cousins acted in Marathi and Gujarati theatre. His sister, Mansi Joshi has appeared in many televisual series.
Sharman Joshi is married to Prerna Chopra, daughter of actor Prem Chopra. The couple has a daughter, Khyana, born in October 2005, and twin boys, Rehan and Varryan, born in July 2009.
He had appeared in role of a deaf character in Gujarati version of popular play, All the Best, which did over 550 shows in three years.He is noted for his free & naturalistic style of acting. His performances are praised as being uninhibited & extremely heartfelt.